Cialis(for treating of male sexual impotence)

ED - polyetiological complex syndrome that may occur due to endocrine, neurological, psychiatric disorders, vascular disease, and others, and lead to reduced efficiency, and social activity of men, an increase of emotional stress, rise depressive disorders. It is one of the most widespread male deseases of nowadays. Cialis can help thousands of men to live with normal sexual life without problems.

Cialis Drug interaction.

Antihypertensive medications. Cialis has a systemic vasodilating action, which may potentiate the hypotensive effect of antihypertensive drugs. In addition, at patients with poorly controlled hypertension receiving multiple antihypertensive agents, perhaps more significant Cialis can decrease blood pressure. In most patients blood pressure reduction is not accompanied by symptoms of hypotension. Those receiving treatment with antihypertensive drugs and taking Cialis, should be given appropriate clinical advice.

alpha-adrenergic blockers. There were no significant blood pressure reduction in patients simultaneously treated with selective blocker Cialkis and ?1-adrenoceptor tamsulosin.

In the application of tadalafil in healthy volunteers treated with blocker of ?1-adrenergic receptors doxazosin in a dose of 4-8 mg / day, there was noticed enhancement of the hypotensive action. Some patients have reported dizziness.

Alcohol. Cialis did not affect the concentration of ethanol, and ethanol does not affect the concentration of Cialis. In patients receiving high doses of ethanol (0.7 g /kg body weight), concomitant use of Cialis did not cause a statistically significant reduction in blood pressure. Some patients reported postural dizziness and orthostatic hypotension. The use of Cialis on the background of ethanol at lower doses (0.6 g / kg) did not cause the development of hypotension and dizziness was detected with the same frequency as that of taking only of alcohol.

H2-antagonists. Increasing the pH in the stomach as a result of H2-receptor blocker nisatidine has no effect on the pharmacokinetics of Cialis.

Antacids (aluminum hydroxide, magnesium hydroxide). Simultaneous administration of antacids (aluminum hydroxide, magnesium hydroxide) and Cialis reduced its rate of absorption without altering the exposure of AUC of Cialis.

Acetylsalicylic acid. Cialis does not increase bleeding in patients receiving aspirin.

Warfarin. Cialis has no clinically significant effect on the pharmacokinetics of S-warfarin or R-warfarin and has no effect on prothrombin time induced by warfarin.

Theophylline. Cialis has no clinically significant effect on the pharmacokinetics or pharmacodynamics of theophylline.

Incompatibility. Cialis is contraindicated in patients using organic nitrates in any dosage form.